刘冰鑫,女,1998年8月生,山西运城人,工学博士,讲师。现从事环境工程微生物学、环境生物学、环境化学、环境生态工程设计课程的教学工作。研究方向为:环境病原菌防治、噬菌体及其功能蛋白的表达应用。参与完成国家自然科学基金项目面上1项,北京市自然科学基金面上项目1项,国家科技重大专项子课题1项,发表中英文论文累计10余篇,中文发明专利5项。
教育科研经历: 2016.09——2020.06;山西大学环境科学专业,获工学学士学位。 2020.09——2025.06;中国科学院大学环境科学专业硕博连读,获工学博士学位。 2024.01——2025.01;新加坡国立大学杨潞龄医学院,联培博士。 2025.09——至今;长治学院生命科学系讲师。
近年来科研成果: 一、SCI论文: 1.Bingxin Liu, Han Lu, Zong Li, Peihan Yan, Ruyin Liu*, Xinchun Liu*, Expression and biological activity of lytic proteins HolST-3 and LysST-3 of Salmonella phage ST-3, 2021, Microbial Pathogenesis. https://doi.org/10.1016/j.micpath.2022.105624 2.Bingxin Liu, Qiucui Guo, Zong Li, Xiaoxiao Guo, Xinchun Liu*, Bacteriophage Endolysin: A Powerful Weapon to Control Bacterial Biofilms, 2023, Protein Journal. https://doi.org/10.1007/s10930-023-10139-z 3.Bingxin Liu, Zong Li, Qiucui Guo, Xiaoxiao Guo, Ruyin Liu*, Xinchun Liu*, Integration of Lysin into Chitosan Nanoparticles for Improving Bacterial Biofilm Inhibition, 2023, Appl Biochem Biotechnol. https://doi.org/10.1007/s12010-023-04627-2 4.Bingxin Liu*, Zhankun Chang, Zong Li, Ruyin Liu, Xinchun Liu*, Prediction of key amino acids of Salmonella phage endolysin LysST-3 and detection of its mutants’ activity, 2024, Archives of Microbiology. https://doi.org/10.1007/s00203-024-03915-7 5.Zong Li, Bingxin Liu, Bing Cao, Shujuan Cun, Liu Ruyin*, Liu Xinchun*, The potential role of viruses in antibiotic resistance gene dissemination in activated sludge viromes, 2025, Journal of Hazardous Materials. https://doi.org/10.1016/j.jhazmat.2024.137046 6.Guo Qiucui, Liu Bingxin, Guo Xiaoxiao, Liu Ruyin*, Liu Xinchun*, Characterization and application of LysSGF2 and HolSGF2 as potential biocontrol agents against planktonic and biofilm cells of common pathogenic bacteria, 2024, International Journal of Food Microbiology. https://doi.org/10.1016/j.ijfoodmicro.2024.110848 7.Zhankun Chang , Bingxin Liu , Han Lu , Qiucui Guo , Zong Li , Ruyin Liu*, Xinchun Liu*, Cloning and characterization of the lysis protein LysSGF3 from Shigella Microviridae phage SGF3 for control of pathogenic bacteria and biofilms, 2025, International Journal of Biological Macromolecules, https://doi.org/10.1016/j.ijbiomac.2025.144676 8.Wenbin Xiong, Bingxin Liu*, Han Lu, Xinchun Liu*, Two novel bacteriophages isolated from the environment that can help control activated sludge foaming, 2024, Folia Microbiologica. https://doi.org/10.1007/s12223-024-01145-4 9.Lu Min, Liu Bingxin, Xiong Wenbin, Liu Xinchun*, The Combination of Salmonella Phage ST-3 and Antibiotics to Prevent Salmonella Typhimurium In Vitro, 2022, Current Microbiology. https://doi.org/10.1007/s00284-022-03073-3 10.Zong Li, Xiaoxiao Guo, Bingxin Liu, Ting Huang, Ruyin Liu*, Xinchun Liu*, Metagenome sequencing reveals shifts in phage-associated antibiotic resistance genes from influent to effluent in wastewater treatment plants, 2024, Water Research. https://doi.org/10.1016/j.watres.2024.121289 二、中文发明专利: 一种沙门氏菌噬菌体裂解酶LysST-3及其应用:CN 116286765 A;刘新春,刘冰鑫,郭秋翠,闫沛涵。 一种噬菌体裂解酶壳聚糖纳米粒及其制备方法与应用:CN 116211826 A;刘新春,刘冰鑫,郭秋翠,闫沛涵。 一种裂解志贺氏菌的裂解蛋白基因及其应用:CN 119410612A;刘新春,常占坤,郭秋翠,刘冰鑫。 一种穿孔素HolSGF2及其制备方法和应用:CN 117510594A;刘新春,郭秋翠,郭潇潇,刘冰鑫。 一株纤维微菌噬菌体DS1及其应用:CN 119506227A;刘如铟,刘新春,彭庆收,闫沛涵,刘冰鑫。
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